AddImputedScore: Calculate imputed expression values

In nukappa/seurat_v2: Seurat : R toolkit for single cell genomics

Description

Uses L1-constrained linear models (LASSO) to impute single cell gene expression values.

Usage

AddImputedScore(object, genes.use = NULL, genes.fit = NULL, s.use = 20,
  do.print = FALSE, gram = TRUE)

Arguments

object	Seurat object
genes.use	A vector of genes (predictors) that can be used for building the LASSO models.
genes.fit	A vector of genes to impute values for
s.use	Maximum number of steps taken by the algorithm (lower values indicate a greater degree of smoothing)
do.print	Print progress (output the name of each gene after it has been imputed).
gram	The use.gram argument passed to lars

Value

Returns a Seurat object where the imputed values have been added to object@data

nukappa/seurat_v2 documentation built on May 24, 2019, 9:57 a.m.