rmpiro/decompTumor2Sig: Decomposition of individual tumors into mutational signatures by signature refitting
Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.
Getting started
Browse package contents
Package details |
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| Bioconductor views | BiologicalQuestion BiomedicalInformatics DNASeq Genetics GenomicVariation SNP Sequencing Software SomaticMutation StatisticalMethod |
| Maintainer | |
| License | GPL-2 |
| Version | 2.13.1 |
| URL | http://rmpiro.net/decompTumor2Sig/ https://github.com/rmpiro/decompTumor2Sig |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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