rmpiro/decompTumor2Sig: Decomposition of individual tumors into mutational signatures by signature refitting

Uses quadratic programming for signature refitting, i.e., to decompose the mutation catalog from an individual tumor sample into a set of given mutational signatures (either Alexandrov-model signatures or Shiraishi-model signatures), computing weights that reflect the contributions of the signatures to the mutation load of the tumor.

Getting started

Package details

Bioconductor views BiologicalQuestion BiomedicalInformatics DNASeq Genetics GenomicVariation SNP Sequencing Software SomaticMutation StatisticalMethod
URL http://rmpiro.net/decompTumor2Sig/ https://github.com/rmpiro/decompTumor2Sig
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
rmpiro/decompTumor2Sig documentation built on May 15, 2022, 3:27 a.m.