matchDesign: normalize Infinium I probe betas to Infinium II
In zwdzwd/sesame: SEnsible Step-wise Analysis of DNA MEthylation BeadChips
matchDesign R Documentation
normalize Infinium I probe betas to Infinium II
Description
This is designed to counter tail inflation in Infinium I probes.
Usage
matchDesign(sdf, min_dbeta = 0.3)
Arguments
sdf
SigDF
min_dbeta
the default algorithm perform 2-state
quantile-normalization of the unmethylated and methylated modes
separately. However, when the two modes are too close, we fall back
to a one-mode normalization. The threshold defines the maximum
inter-mode distance.
Value
SigDF
Examples
library(RPMM)
sdf <- sesameDataGet("MM285.1.SigDF")
sesameQC_plotBetaByDesign(sdf)
sesameQC_plotBetaByDesign(matchDesign(sdf))
zwdzwd/sesame documentation built on Dec. 21, 2024, 1:20 p.m.
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| matchDesign | R Documentation |
normalize Infinium I probe betas to Infinium II
Description
This is designed to counter tail inflation in Infinium I probes.
Usage
matchDesign(sdf, min_dbeta = 0.3)
Arguments
sdf |
SigDF |
min_dbeta |
the default algorithm perform 2-state quantile-normalization of the unmethylated and methylated modes separately. However, when the two modes are too close, we fall back to a one-mode normalization. The threshold defines the maximum inter-mode distance. |
Value
SigDF
Examples
library(RPMM)
sdf <- sesameDataGet("MM285.1.SigDF")
sesameQC_plotBetaByDesign(sdf)
sesameQC_plotBetaByDesign(matchDesign(sdf))
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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