twoCompsEst2: Estimate the fraction of the 2nd component in a 2-component...

In zwdzwd/sesame: SEnsible Step-wise Analysis of DNA MEthylation BeadChips

Estimate the fraction of the 2nd component in a 2-component mixture

Description

Estimate the fraction of the 2nd component in a 2-component mixture

Usage

twoCompsEst2(
  pop1,
  pop2,
  target,
  use.ave = TRUE,
  diff_1m2u = NULL,
  diff_1u2m = NULL
)

Arguments

pop1	Reference methylation level matrix for population 1
pop2	Reference methylation level matrix for population 2
target	Target methylation level matrix to be analyzed
use.ave	use population average in selecting differentially methylated probes
diff_1m2u	A vector of differentially methylated probes (methylated in population 1 but unmethylated in population 2)
diff_1u2m	A vector of differentially methylated probes (unmethylated in population 1 but methylated in population 2)

Value

Estimate of the 2nd component in the 2-component mixture

zwdzwd/sesame documentation built on Nov. 11, 2024, 9:33 a.m.