lambdaPWM: Accessor Method for the 'lambdaPWM' slot in a...

Description Usage Arguments Details Value Author(s) References Examples

Description

Accessor Method for the lambdaPWM slot in a parameterOptions object

Usage

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lambdaPWM(object)

Arguments

object

object is parameterOptions object

Details

The model underlying ChIPanalyser internally infers two paramters: number of bound molecules and lambda. Lambda represents a scaling factor for the Position weight matrix (PWM). This can be described as how well does a TF discriminate between high affinity and very high affinity sites.

Value

Returns the value assigned to the lambdaPWM slot in a parameterOptions object.

Author(s)

Patrick C. N. Martin <p.martin@essex.ac.uk>

References

Zabet NR, Adryan B (2015) Estimating binding properties of transcription factors from genome-wide binding profiles. Nucleic Acids Res., 43, 84<e2><80><93>94.

Examples

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# Loading data
data(ChIPanalyserData)

#Building data objects
GPP <- parameterOptions(lambdaPWM=1)
#Setting new Value for lambdaPWM
lambdaPWM(GPP)

ChIPanalyser documentation built on Nov. 8, 2020, 8:23 p.m.