Shift and scaling normalization of Illumina Infinium methylation data at probe level

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Description

Shift and scaling normalization of Illumina Infinium methylation data at probe level

Usage

1
normalizeMethylation.ssn(methyLumiM, separateColor = FALSE)

Arguments

methyLumiM

a MethyLumiM object includes Illumina Infinium methylation data

separateColor

determine whether separately normalize two color channels

Value

Return an object (same class as input methyLumiM) with updated "methylated" and "unmethylated" data matrix after background level adjustment.

Author(s)

Pan DU

See Also

See Also lumiMethyN, and normalizeMethylation.quantile

Examples

1
2
data(example.lumiMethy)
lumiMethy.norm = normalizeMethylation.ssn(example.lumiMethy)

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