Estimate methylation Beta-value matrix
Estimate methylation Beta-value matrix from MethyLumiM-class object or eSet-class object, which include methylated and unmethylated probe intensities
MethyLumiM-class object or eSet-class object, which include methylated and unmethylated probe intensities
determine whether return an ExpressionSet or matrix object
An offset value added to the denominator to avoid close to zero intensities
Beta-value is ratio between Illumina methylated probe intensity and total probe intensities (sum of methylated and unmethylated probe intensities, see
estimateIntensity). An offset value added to the denominator to avoid close to zero intensities in the denominator. Beta-value is in the range of 0 and 1. If we assume the probe intensity follows Gamma distribution, then the Beta-value follows a Beta distribution.
An ExpressionSet or matrix object of methylation Beta-value
See Also as
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