readIMGT | R Documentation |
readIMGT
read in IMGT databaseLoads all reference germlines from an Immcantation-formatted IMGT database.
readIMGT(dir, quiet = FALSE)
dir |
directory containing Immcantation-formatted IMGT database |
quiet |
print warnings? |
Input directory must be formatted to Immcantation standard. See https://changeo.readthedocs.io/en/stable/examples/igblast.html for example of how to download.
List of lists, leading to IMGT-gapped nucleotide sequences. Structure of object is list[[locus]][[segment]] locus refers to locus (e.g. IGH, IGK, TRA) segment refers to gene segment caegory (V, D, or J)
# vdj_dir contains a minimal example of reference germlines
# (IGHV3-11*05, IGHD3-10*01 and IGHJ5*02)
# which are the gene assignments for ExamapleDb[1,]
vdj_dir <- system.file("extdata", "germlines", "imgt", "human", "vdj", package="dowser")
imgt <- readIMGT(vdj_dir)
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