LawlorPancreasData: Obtain the Lawlor pancreas data

In LTLA/scRNAseq: Collection of Public Single-Cell RNA-Seq Datasets

Obtain the Lawlor pancreas data

Description

Provides the human pancreas single-cell RNA-seq data from Lawlor et al. (2017).

Usage

LawlorPancreasData(legacy = FALSE)

Arguments

legacy

Logical scalar indicating whether to pull data from ExperimentHub. By default, we use data from the gypsum backend.

Details

Column metadata is provided in the same form as supplied in GSE86469. This contains information such as the cell type labels and patient status.

All data are downloaded from ExperimentHub and cached for local re-use. Specific resources can be retrieved by searching for scRNAseq/lawlor-pancreas.

Value

A SingleCellExperiment object with a single matrix of read counts.

Author(s)

Aaron Lun

References

Lawlor N et al. (2017). Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes. Genome Res. 27(2), 208-222.

Examples

sce <- LawlorPancreasData()

LTLA/scRNAseq documentation built on June 28, 2024, 7:31 p.m.