fit_cmp_mods: Fits model scaling total CMPs to metabolite concentrations

In borenstein-lab/mimosa2: Model-based Integration of Metabolite Observations and Species Abundances

Fits model scaling total CMPs to metabolite concentrations

Description

Fits model scaling total CMPs to metabolite concentrations

Usage

fit_cmp_mods(
  species_cmps,
  mets_melt,
  rank_based = F,
  rank_type = "Rfit",
  cmp_nonzero_min = 4,
  FDRcorrect = T
)

Arguments

species_cmps	Table of species contribution abundances
mets_melt	Table of metabolite concentrations
rank_based	Whether to use Rfit instead of standard linear regression
rank_type	Type of robust regression to use (Rfit or mblm)
cmp_nonzero_min	Filter metabolites that have fewer than this number of nonzero CMP scores
FDRcorrect	Whether to include a column of FDR-corrected p-values

Value

List of 2 data.tables - one with model summary results, one with model residuals

Examples

fit_cmp_mods(species_cmps, met_data)

borenstein-lab/mimosa2 documentation built on Dec. 19, 2024, 12:44 a.m.