findICG: findICG

findICGR Documentation

findICG

Description

Identifies cell-to-cell Interaction Changed Features (ICF), i.e. genes that are differentially expressed due to interaction with other cell types.

Usage

findICG(...)

Arguments

...

Arguments passed on to findICF

gobject

giotto object

feat_type

feature type

spat_unit

spatial unit

expression_values

expression values to use

selected_feats

subset of selected features (optional)

cluster_column

name of column to use for cell types

spatial_network_name

name of spatial network to use

minimum_unique_cells

minimum number of target cells required

minimum_unique_int_cells

minimum number of interacting cells required

diff_test

which differential expression test

mean_method

method to use to calculate the mean

offset

offset value to use when calculating log2 ratio

adjust_method

which method to adjust p-values

nr_permutations

number of permutations if diff_test = permutation

exclude_selected_cells_from_test

exclude interacting cells other cells

do_parallel

run calculations in parallel with mclapply

set_seed

set a seed for reproducibility

seed_number

seed number

See Also

findICF


drieslab/Giotto_site_suite documentation built on April 26, 2023, 11:51 p.m.