cluster.geneSelection: Selecting genes for cell cluster identification

In minzheguo/SINCERA: An R implementation of SINCERA pipeline for processing single-cell RNA-seq data.

Description

Currently support the specificity metric (Guo et al., PLoS Comp Bio 2015); other metrics will be supported soon

Usage

cluster.geneSelection(object, method = "specificity", pergroup = TRUE,
  min.samples = 2, specifity.thresh = 0.7, do.plot = T, ...)

Arguments

object	A sincera object
method	The selection method, possible values include specificity
pergroup	If TRUE, calculate metrics for each cell groups (samples)
specifity.thresh	The specificity threshold
do.plot	If TRUE, plot figures of selection
min.sample	The selected genes must pass the selection criteria in at least min.sample samples

Value

The updated sincera object with the selected genes in the genes.forclustering slot

minzheguo/SINCERA documentation built on Feb. 3, 2021, 2:31 p.m.