exprs.synthetic.similarity: Calculating the similarity between each gene profile and...

Description Usage Arguments Value

View source: R/signature.R

Description

Calculating the similarity between each gene profile and group specific synthetic reference expression profile synthetic profile is created by setting fpkm(cluster cells)=1, fpkm(non cluster cells)=0

Usage

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exprs.synthetic.similarity(ES, group.by = CLUSTER.LABEL, groups = NULL,
  syn.sim.prefix = SYN.SIM.PREFIX)

Arguments

ES

(ExpressionSet) an ExpressionSet object containing the single cell RNA-seq data

group.by

(character) the name of the column that contains the cluster information

groups

(character) the clusters for signature prediction

syn.sim.prefix

(character) prefix for labeling the columns encoding the results of synthetic profile similarity metric for each group

Value

an ExpressionSet object containing the results of synthetic profile similarity metrics in the attributes of fData


minzheguo/SINCERA documentation built on Feb. 3, 2021, 2:31 p.m.