exprs.specificity: Per group expression specificity calculation

In minzheguo/SINCERA: An R implementation of SINCERA pipeline for processing single-cell RNA-seq data.

Description

Per group expression specificity calculation

Usage

exprs.specificity(ES, group.by = SAMPLE.LABEL, groups = NULL,
  specificity.prefix = EXPR.SPECIFICITY.PREFIX)

Arguments

ES	(ExpressionSet) an ExpressionSet object containing the single cell RNA-seq data
group.by	(character) the name of the column that contains the sample information
groups	(character) samples for measuring specificity
specificity.prefix	(character) the prefix for labeling the columns encoding the results of expression specificity calculation for each group

Details

if a gene has zero expression across all cells, its specificity is zero

Value

an ExpressionSet object with calculated specificities encoded in fData attributes

Note

This function is from SINCERA version a10242015. It will be upgraded soon.

minzheguo/SINCERA documentation built on Feb. 3, 2021, 2:31 p.m.