RSAfromNSA: Directly compute relative specific activity from...

In mooredf22/protlocassign0p1p1: Compute constrained proportional assignments for fractionated protein abundance

Description

Directly compute relative specific activity from protProfileSummary (or from markerProfiles)

Usage

RSAfromNSA(NSA, NstartMaterialFractions, totProt = NULL)

Arguments

NSA	A matrix giving the specific amount or normalized specific amount profiles, either marker profiles from 'cpaSetup' (which requires normalized specific amounts as input), or a list of many protein profiles
NstartMaterialFractions	Number of differential fractions, typically 6, for N, M, L1, L2, P, and S
totProt	Total protein counts in each of the fractions; this is necessary to compute RSA's

Value

rsa: relative specific activity

Examples

data(protNSA_test)
data(totProtAT5)
protAcup <- AcupFromNSA(protNSA_test[,seq_len(9)], NstartMaterialFractions = 9, totProt=totProtAT5)
protRSA <- RSAfromAcup(protAcup, NstartMaterialFractions = 9, totProt=totProtAT5)
protNSA <- NSAfromRSA(protRSA)
all.equal(protNSA, protNSA_test[,seq_len(9)] )

mooredf22/protlocassign0p1p1 documentation built on Feb. 7, 2022, 1:55 a.m.