randomXData <- function(nValues = 30000, nRow = 500, seed = 1985) {
set.seed(seed)
matrix(rnorm(nValues), nrow = nRow)
}
prepareMAE <- function(maxRows = NULL) {
tmpEnv <- new.env()
data("miniACC", package = "MultiAssayExperiment", envir = tmpEnv)
xdata <- tmpEnv$miniACC
if (!is.null(maxRows)) xdata <- xdata[, 1:maxRows]
eventIx <- which(!is.na(
MultiAssayExperiment::colData(xdata)$days_to_death
))
censIx <- which(!is.na(
MultiAssayExperiment::colData(xdata)$days_to_last_followup
))
xdata$surv_event_time <- array(
NA_integer_, nrow(MultiAssayExperiment::colData(xdata))
)
xdata$surv_event_time[eventIx] <- xdata$days_to_death[eventIx]
xdata$surv_event_time[censIx] <- xdata$days_to_last_followup[censIx]
# Keep only valid individuals
validIx <- as.vector(
!is.na(xdata$surv_event_time) &
!is.na(xdata$vital_status) &
xdata$surv_event_time > 0
)
xdataValid <- xdata[
, rownames(MultiAssayExperiment::colData(xdata))[validIx]
]
ydataValid <- MultiAssayExperiment::colData(
xdataValid
)[, c("surv_event_time", "vital_status")]
colnames(ydataValid) <- c("time", "status")
list(xdata = xdataValid, ydata = ydataValid)
}
prepareMockInteractions <- function() {
dplyr::tibble(
protein1 = c(
"9606.ENSP00000000233", "9606.ENSP00000000234",
"9606.ENSP00000000235", "9606.ENSP00000000236",
"9606.ENSP00000000237"
),
protein2 = c(
"9606.ENSP00000272298", "9606.ENSP00000253401",
"9606.ENSP00000401445", "9606.ENSP00000418915",
"9606.ENSP00000327801"
),
neighborhood = 0,
neighborhood_transferred = 0,
fusion = 0,
cooccurence = c(332, 0, 0, 0, 0),
homology = 0,
coexpression = c(0, 0, 0, 0, 69),
coexpression_transferred = c(62, 0, 0, 61, 61),
experiments = 0,
experiments_transferred = c(181, 186, 160, 158, 78),
database = 0,
database_transferred = 0,
textmining = c(0, 0, 0, 542, 0),
textmining_transferred = c(125, 56, 0, 0, 89),
combined_score = c(490, 198, 159, 606, 167)
)
}
prepareOvarian <- function(columns = c("age", "resid.ds")) {
list(
xdata = survival::ovarian[, columns],
ydata = data.frame(
time = survival::ovarian$futime,
status = survival::ovarian$fustat
)
)
}
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