CalcGeneModuleEffect: Calculate effect of perturbations on gene modules

In yanwu2014/perturbLM: A lightweight R package that uses linear models to analyze the effects of chemical/genetic perturbations, conditions, and disease states on single gene expression.

Calculate effect of perturbations on gene modules

Description

Calculate effect of perturbations on gene modules

Usage

CalcGeneModuleEffect(
  coefs.matrix,
  gene.clusters.list,
  gene.module.mapping = NULL,
  min.coef = 0.025
)

Arguments

coefs.matrix	Regression coefficients matrix
gene.clusters.list	List of gene clusters
gene.module.mapping	Mapping gene modules to descriptions
min.coef	Minimum cofficient magnitude for a gene to be considered

Value

Matrix of perturbation effects on each gene modules

yanwu2014/perturbLM documentation built on Aug. 24, 2023, 2:28 p.m.