GroupClusterComp: Get cluster composition of each perturbation

In yanwu2014/perturbLM: A lightweight R package that uses linear models to analyze the effects of chemical/genetic perturbations, conditions, and disease states on single gene expression.

Get cluster composition of each perturbation

Description

Get cluster composition of each perturbation

Usage

GroupClusterComp(
  groups,
  clusters,
  samples = NULL,
  stabilize.var = TRUE,
  ctrl.group = NULL
)

Arguments

groups	Perturbation dictionary (in list format) or vector
clusters	Cluster annotations
samples	Samples (i.e. mice, patients, biological replicates, default: NULL)
stabilize.var	Apply variance stabilizing transformation (default: TRUE)
ctrl.group	Control perturbation to compute logFC against (for paired samples only, default: NULL)

Value

Dataframe of cluster compositions or logFCs for each perturbation

yanwu2014/perturbLM documentation built on Aug. 24, 2023, 2:28 p.m.