DRE-class: An S4 class representing a dose-response experiment of an...

In ybukhman/SynergyScreen: Analyze and simulate synergy screen data

Description

An S4 class representing a dose-response experiment of an individual compound or a mixture

Slots

name

dose-response experiment name, character

compound.name

vector of compound names, character

fraction

vector of compound fractions, numeric, should add up to 1

dose

vector of doses, numeric

response

vector of responses, e.g. OD, numeric

control.response

vector of [untreated] control responses, numeric

effect

fractional effect of the drug(s), can range from 0 for untreated control to 1 for complete growth inhibition

model

named list of fitted models of the dose-response curve, list of objects of class DRModel

ic25

IC25 value inferred from the model, numeric

ic50

IC50 value inferred from the model, numeric

ic75

IC75 value inferred from the model, numeric

true.ic50

"true" IC50 value, can be set for simulation purposes, numeric

true.m

"true" slope parameter of the Hill's equation, can be set for simulation purposes, numeric

comment

a vector of diagnostic messages and other comments, character

dilution.factor

dilution factor, defined for exponential dose series

Examples

data(sim15_screen3)
dre(sim15_screen3,"Cpd1")
plot(dre(sim15_screen3,"Cpd1"))

ybukhman/SynergyScreen documentation built on May 4, 2019, 2:31 p.m.