ScreenDesign-class: S4 class for a synergy screen design

In ybukhman/SynergyScreen: Analyze and simulate synergy screen data

Description

A ScreenDesign class object contains a special data frame specifying design of a screen, i.e. what goes into each well of a set of plates.

Details

Initial implementation supports 96-well, 8*12 plates and mixtures of 2 compounds. Plate rows should be named A-H and columns 1-12. Design data frame must contain the following columns:

1. plate plate identifier

2. column column number, numeric, integer between 1 and 12

3. row row, character or factor with values or levels A-H

4. experiment experiment name, character or factor

5. cpd1 compound 1 name, character or factor

6. dose1 compound 1 dose, numeric

7. cpd2 compound 2 name, character or factor

8. dose2 compound 2 dose, numeric

Additional columns are allowed and will be ignored by SynergyScreen software. Correctness of the data frame structure is verified by a validity method and can be checked by calling validObject().

See Also

data.frame, validObject

Examples

data(sim15_screen3)
head(design(sim15_screen3),n=30)  
str(design(sim15_screen3))

ybukhman/SynergyScreen documentation built on May 4, 2019, 2:31 p.m.