plot-SynergyScreen-missing-method: Plot a SynergyScreen object.

In ybukhman/SynergyScreen: Analyze and simulate synergy screen data

Description

Plot matrix of pairwise interaction index values for a synergy screen.

Usage

## S4 method for signature 'SynergyScreen,missing'
plot(x, y, effect = 0.5, model = "menls",
  ...)

Arguments

x	a SynergyScreen object
y	no parameter y is defined for this method
effect	numeric, fractional effect value to plot the matrix for
model	name of the growth curve model to use, character
...	additional arguments passed to the heatmap function

Details

The matrix visualizes log2(interaction index) values for the specified effect size. The values are visualized on a red-yellow-blue color scale, red indicating synergy, yellow no interaction and blue antagonism.

The index is visualized on log scale because it is a sum of two ratios. Distributions of ratios are highly assymetrical, e.g. 0 to infinity with a mode around 1 Log transform is commonly used to normalize them.

See Also

SynergyScreen, heatmap

Examples

data(sim15_screen3)
plot(sim15_screen3)

ybukhman/SynergyScreen documentation built on May 4, 2019, 2:31 p.m.