initialize-SynergyExperiment-method: Initialise a SynergyExperiment object
In ybukhman/SynergyScreen: Analyze and simulate synergy screen data

Description Usage Arguments Details Value See Also Examples

Create a new SynergyExperiment object from appropriate DRE objects, making sure they form a coherent experiment

1
2
3

## S4 method for signature 'SynergyExperiment'
initialize(.Object, name = NULL,
  mixture.dre.name, compound.dre.name, dre.list)

`.Object`	object of class SynergyExperiment
`name`	optional name of the experiment, character
`mixture.dre.name`	name of the mixture dose-response experiment included in the synergy experiment, character
`compound.dre.name`	names of individual compound dose-response experiments that are included in the synergy experiment, character
`dre.list`	object of class DREList or list of DRE objects

A single ray experiment is assumed in the current implementation, i.e. there should be only one mixture dose-response experiment. There should also be 2 or more compound dose-response experiments.

The dre.list argument is used to check that compound.dre.name and mixture.dre.name refer to valid dose-response experiments and make sure compounds are listed in the same order in the synergy experiment object as in the corresponding mixture dose-response experiment.

SynergyExperiment object

DRE

1
2
3

data(sim15_screen3)
new("SynergyExperiment", name="Cpd1-Cpd2", mixture.dre.name="Cpd1-Cpd2", 
    compound.dre.name=c("Cpd1","Cpd2"), dre_list(sim15_screen3))