effectiveDose: Compute the dose that causes specified fractional effect

In ybukhman/SynergyScreen: Analyze and simulate synergy screen data

Description

Take a DRE (dose-response experiment) object and compute the dose that causes the specified fractional effect

Usage

effectiveDose(dre, effect, model = "menls")

Arguments

dre	a DRE object
effect	fractional effect value, numeric
model	name of the model to use, character

Details

effect value should be between 0 and 1, e.g. 0.5 to compute interaction index at IC50, 0.25 to compute IC25 (25 Corresponding value of the response variable is defined as control.response*(1-effect)

If the effect is not achieved by doses between 0 and max dose for the dose-response experiment, effectiveDose produces a warning and returns NA

Value

dose value that causes the effect, numeric

See Also

DRE

Examples

data(sim15_screen3)
effectiveDose(dre(sim15_screen3,"Cpd1"),0.5)

ybukhman/SynergyScreen documentation built on May 4, 2019, 2:31 p.m.