Description Usage Arguments Details Value Methods (by class) See Also Examples
Synergy is measured as interaction index. This function computes values of the interaction index for a set effective dose values for each synergy experiment in a screen.
1 2 3 4 5 6 | computeSynergies(object, ...)
## S4 method for signature 'SynergyScreen'
computeSynergies(object, effect = c(0.25, 0.5,
0.75), model = "menls", control.weight = 10, span = 1, silent = T,
...)
|
object |
object of class SynergyScreen |
... |
other arguments passed to the model-fitting function, e.g. to loess or nls |
effect |
numeric vector of effects, between 0 and 1 |
model |
character vector of model types. Supported types include melm, menls and loess |
control.weight |
weight to assing to the control.response, numeric |
span |
span parameter for loess, numeric |
silent |
logical: should warnings and error messages be suppressed? |
See description of model types in fit
A SynergyScreen object with @synergies slot populated by a data frame of interaction index values
SynergyScreen
: Compute synergies in a screen
1 2 3 |
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