metagenomeSeq: Statistical analysis for sparse high-throughput sequencing

metagenomeSeq is designed to determine features (be it Operational Taxanomic Unit (OTU), species, etc.) that are differentially abundant between two or more groups of multiple samples. metagenomeSeq is designed to address the effects of both normalization and under-sampling of microbial communities on disease association detection and the testing of feature correlations.

Package details

AuthorJoseph Nathaniel Paulson, Nathan D. Olson, Domenick J. Braccia, Justin Wagner, Hisham Talukder, Mihai Pop, Hector Corrada Bravo
Bioconductor views Classification Clustering DifferentialExpression GeneticVariability ImmunoOncology Metagenomics Microbiome MultipleComparison Normalization Sequencing Software Visualization
MaintainerJoseph N. Paulson <>
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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metagenomeSeq documentation built on Nov. 8, 2020, 5:34 p.m.