S4 class that holds parameters for the Lun2 simulation.
The Lun2 simulation uses the following parameters:
The number of genes to simulate.
The number of cells to simulate.
Seed to use for generating random numbers.
data.frame containing gene
parameters with two coloumns:
Mean (mean expression for
each gene) and
Disp (dispersion for each gene).
zero-inflated gene parameters with three coloumns:
(mean expression for each gene),
Disp (dispersion for
each, gene), and
Prop (zero proportion for each gene).
The number of plates to simulate.
Character vecotor giving the plates considered to be part of the "ingroup".
Plate effect modifier factor. The plate effect variance is divided by this value.
Plate effect variance.
Factor giving the plate that each cell comes from.
Library size for each cell.
Modifier factor for library sizes. The library sizes are multiplied by this value.
Number of differentially expressed genes.
Fold change for differentially expressed genes.
The parameters not shown in brackets can be estimated from real data using
lun2Estimate. For details of the Lun2 simulation see
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