mfaSimulate: MFA simulation

Description Usage Arguments Details Value References Examples

View source: R/mfa-simulate.R

Description

Simulate a bifurcating pseudotime path using the mfa method.

Usage

1
mfaSimulate(params = newMFAParams(), verbose = TRUE, ...)

Arguments

params

MFAParams object containing simulation parameters.

verbose

Logical. Whether to print progress messages.

...

any additional parameter settings to override what is provided in params.

Details

This function is just a wrapper around create_synthetic that takes a MFAParams, runs the simulation then converts the output from log-expression to counts and returns a SingleCellExperiment object. See create_synthetic and the mfa paper for more details about how the simulation works.

Value

SingleCellExperiment containing simulated counts

References

Campbell KR, Yau C. Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers. Wellcome Open Research (2017).

Paper: 10.12688/wellcomeopenres.11087.1

Code: https://github.com/kieranrcampbell/mfa

Examples

1
sim <- mfaSimulate()

Oshlack/splatter documentation built on June 27, 2018, 10:09 p.m.