Simulate a bifurcating pseudotime path using the mfa method.
MFAParams object containing simulation parameters.
Logical. Whether to print progress messages.
any additional parameter settings to override what is provided in
This function is just a wrapper around
that takes a
MFAParams, runs the simulation then converts the
output from log-expression to counts and returns a
SingleCellExperiment object. See
create_synthetic and the mfa paper for more details about
how the simulation works.
SingleCellExperiment containing simulated counts
Campbell KR, Yau C. Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers. Wellcome Open Research (2017).
sim <- mfaSimulate()
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