kersplatSimCounts: Simulate Kersplat final counts

In Oshlack/splatter: Simple Simulation of Single-cell RNA Sequencing Data

Simulate Kersplat final counts

Description

Simulate the final counts matrix for a Kersplat simulation

Usage

kersplatSimCounts(sim, params, verbose)

Arguments

sim	SingleCellExperiment containing simulation.
params	KersplatParams object with simulation parameters.
verbose	logical. Whether to print progress messages

Details

The cell counts matrix and ambient counts matrix are added together. The result is then downsampled to the cell library size (for cells and doublets) or the ambient library size (for empty cells) using the downsampleMatrix function.

Value

SingleCellExperiment with counts matrix

See Also

downsampleMatrix

Oshlack/splatter documentation built on Dec. 10, 2024, 3:48 p.m.