Description Usage Arguments Value
Calculate the ROGUE value of each putative cluster for each sample.
1 |
expr |
The expression matrix. Rows should be genes and columns should be cells. |
labels |
A vector of cell cluster lables for all cells corresponding to 'expr' argument. |
samples |
A vector of samples (e.g. patients) to which each cell belongs, corresponding to 'expr' argument. |
min.cell.n |
Only clusters containing at least this many cells will receive ROGUE values. |
remove.outlier.n |
Remove this many outlier cells when calculating ROGUE. |
span |
The parameter α which controls the degree of smoothing. |
r |
A small fixed value to avoid log(0) of mean gene expression levels. The default value of r is set to 1, but can also be set to other values such as 0.1 and 0.01. |
filter |
Logical, whether to filter out low-abundance genes and low-quality cells. |
min.cells |
if parameter filter is "TRUE", include genes detected in at least this many cells. |
min.genes |
if parameter filter is "TRUE", Include cells where at least this many genes are detected. |
mt.method |
The multiple testing method used in p.adjust. |
A dataframe where rows represent samples, cols represent clusters, and values represent corresponding ROGUEs.
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