countProb: Calculate probability of a genomic region having WW, CC or WC...

In daewoooo/primatR: What the Package Does (TODO)

Calculate probability of a genomic region having WW, CC or WC state.

Description

Exports most likely strand state (WW, CC or WC) based on counts of plus and minus reads and allowed level of background 'alpha'.

Usage

countProb(minusCounts, plusCounts, alpha = 0.1, log = FALSE)

Arguments

minusCounts	Minus (Watson) read counts aligned to PacBio reads.
plusCounts	Plus (Crick) read counts aligned to PacBio reads.
alpha	Estimated level of background in Strand-seq reads.

Value

A matrix of binomial probabilities for a given counts of plus and minus reads for a single cell. (rows=reads/genomic segments, cols=strand states)

Author(s)

David Porubsky, Maryam Ghareghani

daewoooo/primatR documentation built on Oct. 22, 2024, 9:41 p.m.