View source: R/genotypeRegions.R
getGenotype | R Documentation |
Based on directional Strand-seq reads from a genomic region reports most likely genotype based on binomial probabilites of allowed strand states (WW, CC or WC).
getGenotype(gr, min.reads = 5, alpha = 0.05)
gr |
A |
min.reads |
Minimal number of reads to pursue genotyping. |
alpha |
Estimated level of background in Strand-seq reads. |
A data.frame
of binomial probabilities for a given counts of plus and minus reads for a single cell. (rows=reads/genomic segments, cols=strand states)
David Porubsky
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