seqImmuCC_LLSR: Source code for the Linear Least Square Regression performed...

In grst/immunedeconv: Methods for immune cell deconvolution

Source code for the Linear Least Square Regression performed in seqImmuCC.

Description

This code is provided by the authors and the method available at: http://218.4.234.74:3200/immune/

Usage

seqImmuCC_LLSR(
  signature,
  SampleData,
  w = NA,
  QN = T,
  sig.scale = F,
  sig.stand = T,
  sample.scale = T,
  log = T
)

Arguments

signature	signature matrix
SampleData	sample expression profile
w	vector to perform weighted least squares
QN	logical. If TRUE expression matrix is quantile normalized
sig.scale	logical. If TRUE, scales the signature matrix
sig.stand	logical.If TRUE, standardizes the signature matrix
sample.scale	logical. If TRUE, scales the sample expression
log	logical. If TRUE, log transforms signature and expression data

Details

The method is described in Chen et al. doi: 10.3389/fimmu.2018.01286

grst/immunedeconv documentation built on Nov. 10, 2023, 1:33 a.m.