calc_rl_connections: Identifies all R / L interactions

In kgellatl/SignallingSingleCell: Network Analysis for single cell RNA sequencing Data (sc-RNASeq)

Description

This function will map all RL interactions

Usage

calc_rl_connections(
  input,
  nodes,
  group_by = FALSE,
  weight_by_proportion = FALSE,
  print_progress = TRUE
)

Arguments

input	the input ex_sc
nodes	the pData variable used in calc_agg_bulk that will be used to place nodes (such as cluster or cell type)
group_by	the pData columns calc_agg_bulk was calculated on to split the networks into independent networks (such as an experimental condition)
weight_by_proportion	if true will multiple ligand mean expression within a node by the proportion of that group

Details

This will use the calc_agg_bulk results to ID networks

Examples

ex_sc_example <- id_rl(input = ex_sc_example)

kgellatl/SignallingSingleCell documentation built on Dec. 29, 2021, 4:12 p.m.