Description Usage Arguments Value
From allele frequency data in the format of midas_merge.py snps it determines which samples and which positions in each sample are quasi-phaseable and makes the corresponding genotype calls.
| 1 2 3 4 5 6 7 8 | qp_genotypes(
  midas_dir,
  midas_dat,
  map = NULL,
  min_depth = 5,
  min_snv_prop = 0.8,
  maf_thres = 0.2
)
 | 
| midas_dir | Directory with outptu from mdas_merge.py snps. Either this or midas_dat needs to be provided. | 
| midas_dat | A list with info, freq, and depth elements corresponding to the result of read_midas_data. Either this or midas_dir needs to be provided | 
| map | A data table associating samples in the MIDAS otput to groups. It must have an 'sample' and a 'Group' column. Only used if midas_dat was passed and only samples in map are processed. | 
| min_depth | Minimum sequence depth at a given sample and position to be abele to call a gnotype | 
| min_snv_prop | Minimum proportion of SNVs in a sample, among SNVs that pass the min_depth filter, that pass the maf_thres filter. Samples that have a smaller proportion of SNVs passing this condition are considered non-quasi-phaseable and genotype calls are not made. | 
| maf_thres | A value in the range [0, 0.5]. SNVs are only considered quasi-phaseable if their frequency (f) fullfills f <= maf_thres | f >= 1 - maf_thres, and if they are in a quasi-phaseable sample. SNVs in quasi-phaseable samples, that do not pass the maf_thres or min_depth filters are considered missing data. | 
A tiblle with columns site_id, and one column per quasi-phaseable sample, which contain the genotype calls.
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