get_fine_mapping: Get Fine Mapping

In gtexr: Query the GTEx Portal API

Get Fine Mapping

Description

Retrieve Fine Mapping Data

• Finds and returns ⁠Fine Mapping⁠ data for the provided list of genes

• By default, this endpoint fetches data from the latest GTEx version

The retrieved data is split into pages with items_per_page entries per page

GTEx Portal API documentation

Usage

get_fine_mapping(
  gencodeIds,
  datasetId = "gtex_v8",
  variantId = NULL,
  tissueSiteDetailIds = NULL,
  page = 0,
  itemsPerPage = 250
)

Arguments

gencodeIds	A character vector of Versioned GENCODE IDs, e.g. c("ENSG00000132693.12", "ENSG00000203782.5").
datasetId	String. Unique identifier of a dataset. Usually includes a data source and data release. Options: "gtex_v8", "gtex_snrnaseq_pilot".
variantId	String. A gtex variant ID.
tissueSiteDetailIds	Character vector of IDs for tissues of interest. Can be GTEx specific IDs (e.g. "Whole_Blood"; use get_tissue_site_detail() to see valid values) or Ontology IDs.
page	Integer (default = 0).
itemsPerPage	Integer (default = 250).

Value

A tibble.

See Also

Other Static Association Endpoints: get_eqtl_genes(), get_independent_eqtl(), get_multi_tissue_eqtls(), get_significant_single_tissue_eqtls(), get_significant_single_tissue_eqtls_by_location(), get_significant_single_tissue_ieqtls(), get_significant_single_tissue_isqtls(), get_significant_single_tissue_sqtls(), get_sqtl_genes()

Examples

## Not run: 
# search by gene
get_fine_mapping(gencodeIds = c("ENSG00000132693.12",
                               "ENSG00000203782.5"))

# optionally filter for a single variant and/or one or more tissues
get_fine_mapping(gencodeIds = c("ENSG00000132693.12",
                               "ENSG00000203782.5"),
                 variantId = "chr1_153228363_A_G_b38",
                 tissueSiteDetailIds = c("Whole_Blood",
                                        "Thyroid"))

## End(Not run)

gtexr documentation built on Sept. 19, 2024, 5:06 p.m.