get_gene_expression: Get Gene Expression

In gtexr: Query the GTEx Portal API

Get Gene Expression

Description

Find normalized gene expression data.

• Returns normalized gene expression in tissues at the sample level.

• Results may be filtered by dataset, gene or tissue, but at least one gene must be provided.

By default, this service queries the latest GTEx release.

GTEx Portal API documentation

Usage

get_gene_expression(
  gencodeIds,
  datasetId = "gtex_v8",
  tissueSiteDetailIds = NULL,
  attributeSubset = NULL,
  page = 0,
  itemsPerPage = 250
)

Arguments

gencodeIds	A character vector of Versioned GENCODE IDs, e.g. c("ENSG00000132693.12", "ENSG00000203782.5").
datasetId	String. Unique identifier of a dataset. Usually includes a data source and data release. Options: "gtex_v8", "gtex_snrnaseq_pilot".
tissueSiteDetailIds	Character vector of IDs for tissues of interest. Can be GTEx specific IDs (e.g. "Whole_Blood"; use get_tissue_site_detail() to see valid values) or Ontology IDs.
attributeSubset	String. Examples include but are not limited to "sex", "ageBracket"
page	Integer (default = 0).
itemsPerPage	Integer (default = 250).

Value

A tibble.

See Also

Other Expression Data Endpoints: get_clustered_median_exon_expression(), get_clustered_median_gene_expression(), get_clustered_median_junction_expression(), get_clustered_median_transcript_expression(), get_expression_pca(), get_median_exon_expression(), get_median_gene_expression(), get_median_junction_expression(), get_median_transcript_expression(), get_single_nucleus_gex(), get_single_nucleus_gex_summary(), get_top_expressed_genes()

Examples

## Not run: 
  # multiple genes, selected tissues
  get_gene_expression(gencodeIds = c("ENSG00000132693.12",
                                     "ENSG00000203782.5"),
                      tissueSiteDetailIds = c("Thyroid", "Whole_Blood"))

  # single gene, selected (single) tissue
  get_gene_expression(gencodeIds = "ENSG00000132693.12",
                      tissueSiteDetailIds = "Whole_Blood")

  # subset by sex
  get_gene_expression(gencodeIds = "ENSG00000132693.12",
                      tissueSiteDetailIds = "Whole_Blood",
                      attributeSubset = "sex")

  # subset by age bracket
  get_gene_expression(gencodeIds = "ENSG00000132693.12",
                      tissueSiteDetailIds = "Whole_Blood",
                      attributeSubset = "ageBracket")

## End(Not run)

gtexr documentation built on Sept. 19, 2024, 5:06 p.m.