View source: R/splat-simulate.R
splatSimDropout | R Documentation |
A logistic function is used to form a relationship between the expression level of a gene and the probability of dropout, giving a probability for each gene in each cell. These probabilities are used in a Bernoulli distribution to decide which counts should be dropped.
splatSimDropout(sim, params)
sim |
SingleCellExperiment to add dropout to. |
params |
SplatParams object with simulation parameters. |
SingleCellExperiment with simulated dropout and observed counts.
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