Simulate counts using the ZINB-WaVE method.
ZINBParams object containing simulation parameters.
logical. Whether to print progress messages
any additional parameter settings to override what is provided in
This function is just a wrapper around
ZINBParams, runs the simulation then converts the
output to a
zinbSim and the ZINB-WaVE paper for
more details about how the simulation works.
SingleCellExperiment containing simulated counts
Campbell K, Yau C. Uncovering genomic trajectories with heterogeneous genetic and environmental backgrounds across single-cells and populations. bioRxiv (2017).
Risso D, Perraudeau F, Gribkova S, Dudoit S, Vert J-P. ZINB-WaVE: A general and flexible method for signal extraction from single-cell RNA-seq data bioRxiv (2017).
sim <- zinbSimulate()
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