Hellman_SimulatedFM1Panel_WES: Dataset containing tumor mutational burden and clinical data...
In acc-bioinfo/TMBleR: Tumor Mutational Burden Quantification From Gene Panels And WES
Description
Usage
Format
Source
Description
Dataset from Hellman et al., Cancer Cell 2018 containing the original
WES-based TMB value and clinical response from the study and a simulated
panel-based TMB value calculated in silico by subsetting the WES dataset to
only contain genes targeted by a custom panel used as example.
Usage
1
Format
A data frame with 74 rows and 4 variables
- PatientID
Patient identifier
- ClinicalResponse
Clinical response to immunotherapy; responder or
nonresponder
- Panel.NumMuts
Panel-based tumor mutational burden, in total number of
mutations
- WES.NumMuts
WES-based tumor mutational burden, in total number of
mutations
Source
provided as supplementary table by Hellman et al. in "Tumor Mutational
Burden and Efficacy of Nivolumab Monotherapy and in Combination With Ipilimumab
in Small-Cell Lung Cancer". Cancer Cell 2018 (PMID: 29731394) and modified to
add simulated panel TMB
acc-bioinfo/TMBleR documentation built on Dec. 18, 2021, 10:21 p.m.
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Description Usage Format Source
Description
Dataset from Hellman et al., Cancer Cell 2018 containing the original WES-based TMB value and clinical response from the study and a simulated panel-based TMB value calculated in silico by subsetting the WES dataset to only contain genes targeted by a custom panel used as example.
Usage
1 |
Format
A data frame with 74 rows and 4 variables
- PatientID
Patient identifier
- ClinicalResponse
Clinical response to immunotherapy; responder or nonresponder
- Panel.NumMuts
Panel-based tumor mutational burden, in total number of mutations
- WES.NumMuts
WES-based tumor mutational burden, in total number of mutations
Source
provided as supplementary table by Hellman et al. in "Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination With Ipilimumab in Small-Cell Lung Cancer". Cancer Cell 2018 (PMID: 29731394) and modified to add simulated panel TMB
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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