HumanTumorSuppressors: List of human tumor suppressors
In acc-bioinfo/TMBleR: Tumor Mutational Burden Quantification From Gene Panels And WES
Description
Usage
Format
Source
Description
List of gene ids known to be human tumor suppressors. It is used as default
tsList argument in applyFilters() if not specified otherwise and the
removeCancer argument is set to TRUE. In such a sceneario, truncating mutations in
these human tumor suppressor genes are not counted for TMB quantification.
This is a corretive strategy usually required for panel-based TMB
quantification to avoid upward skewing bias due to panel enrichment in cancer
genes.
Usage
1
Format
character vector with 1217 elements
Source
From the TSGene 2.0 database available at
https://bioinfo.uth.edu/TSGene/. See Zhao et al. "TSGene 2.0: an
updated literature-based knowledgebase for tumor suppressor genes" NAR 2016.
PMID: 26590405
acc-bioinfo/TMBleR documentation built on Dec. 18, 2021, 10:21 p.m.
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Description Usage Format Source
Description
List of gene ids known to be human tumor suppressors. It is used as default tsList argument in applyFilters() if not specified otherwise and the removeCancer argument is set to TRUE. In such a sceneario, truncating mutations in these human tumor suppressor genes are not counted for TMB quantification. This is a corretive strategy usually required for panel-based TMB quantification to avoid upward skewing bias due to panel enrichment in cancer genes.
Usage
1 |
Format
character vector with 1217 elements
Source
From the TSGene 2.0 database available at https://bioinfo.uth.edu/TSGene/. See Zhao et al. "TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes" NAR 2016. PMID: 26590405
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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