compareTMBdistribution: Compare TMB distribution in responders and nonresponders
In acc-bioinfo/TMBleR: Tumor Mutational Burden Quantification From Gene Panels And WES
Description
Usage
Arguments
Value
Author(s)
Examples
View source: R/compareTMBdistributions.R
Description
This function generates applies the unpaired Mann-Whitney test to compare the
distribution of TMB values between immunotherapy responders and nonresponders.
Usage
1
compareTMBdistribution(dataset, TMB)
Arguments
dataset
a data.frame object with the following fields:
patient identifier, numeric TMB value and response to
immunotherapy, expressed as "responders" or "nonresponders"
TMB
name of the data.frame column containing TMB values
Value
Returns the statistics from Wilcoxon test
Author(s)
Laura Fancello
Examples
1
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## Compare TMB distribution between immunotherapy responders and nonresponders
## using the unpaired Mann-Whitney test
# Read TMB values and response to immunotherapy
data(Hellman_SimulatedFM1Panel_WES)
# Compare TMB distribtions by Wilcoxon test
compareTMBdistribution(dataset = Hellman_SimulatedFM1Panel_WES, TMB = "WES.NumMuts")
acc-bioinfo/TMBleR documentation built on Dec. 18, 2021, 10:21 p.m.
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Description Usage Arguments Value Author(s) Examples
View source: R/compareTMBdistributions.R
Description
This function generates applies the unpaired Mann-Whitney test to compare the distribution of TMB values between immunotherapy responders and nonresponders.
Usage
1 | compareTMBdistribution(dataset, TMB)
|
Arguments
dataset |
a |
TMB |
name of the |
Value
Returns the statistics from Wilcoxon test
Author(s)
Laura Fancello
Examples
1 2 3 4 5 6 7 8 | ## Compare TMB distribution between immunotherapy responders and nonresponders
## using the unpaired Mann-Whitney test
# Read TMB values and response to immunotherapy
data(Hellman_SimulatedFM1Panel_WES)
# Compare TMB distribtions by Wilcoxon test
compareTMBdistribution(dataset = Hellman_SimulatedFM1Panel_WES, TMB = "WES.NumMuts")
|
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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