Description Usage Arguments Value Author(s)
View source: R/removeCancerVariants.R
This function removes from the vcf dataset those variants defined as pathogenic (cancer) in COSMIC or truncating variants in tumor suppressor genes.
1 | removeCancerVariants(vcf, assembly, tsList)
|
vcf |
a |
assembly |
human genome assembly: hg19 or hg38 |
tsList |
path to file containg list of tumor suppressors. If not provided a list of 1217 tumor suppressors from the TSgene2 database is used. |
Returns a data.frame
object containing only those variants
which passed the filter
Laura Fancello
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