fit.ts: Model gene expression levels as a brancing spline function of...

Description Usage Arguments Value

View source: R/crestree.functions.R

Description

Model gene expression levels as a brancing spline function of tree positions.

Usage

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fit.ts(r, X, n.map, n.cores = parallel::detectCores()/2, gamma = 1.5,
  knn = 1)

Arguments

r

pptree object

X

expressinon matrix of genes (rows) vs cells (columns)

n.map

number of probabilistic cell-to-tree mappings to use

gamma

stringency of penalty.

knn

use expression averaging among knn cells

Value

matrix of fitted gene expression levels to the tree


hms-dbmi/crestree documentation built on July 11, 2019, 8:04 p.m.