meffil.normalize.sample: Normalize Infinium HumanMethylation450 BeadChip

View source: R/normalize-sample.r

meffil.normalize.sampleR Documentation

Normalize Infinium HumanMethylation450 BeadChip

Description

Normalize sample methylation data using normalized quantiles.

Usage

meffil.normalize.sample(norm.object, remove.poor.signal = F, verbose = F)

Arguments

norm.object

An element of meffil.normalize.quantiles().

remove.poor.signal

Set methylation values for poorly detected probes to missing (Default: FALSE). Poor signal was identified during QC by meffil.qc() as signal that failed to pass the detection p-value threshold (detection.threshold) or bead threshold (bead.threshold).

verbose

If TRUE, then status messages are printed during execution (Default: FALSE).

Value

List containing normalized methylated and unmethylated signals.


perishky/meffil documentation built on March 20, 2024, 1:56 a.m.