get_top_expressed_genes: Get Top Expressed Genes

In gtexr: Query the GTEx Portal API

Get Top Expressed Genes

Description

Find top expressed genes for a specified tissue.

• Returns top expressed genes for a specified tissue in a dataset, sorted by median expression.

• When the optional parameter filterMtGene is set to true, mitochondrial genes will be excluded from the results. By default, this service queries the latest GTEx release.

GTEx Portal API documentation

Usage

get_top_expressed_genes(
  tissueSiteDetailId,
  datasetId = "gtex_v8",
  filterMtGene = TRUE,
  page = 0,
  itemsPerPage = getOption("gtexr.itemsPerPage"),
  .verbose = getOption("gtexr.verbose"),
  .return_raw = FALSE
)

Arguments

tissueSiteDetailId	String. The ID of the tissue of interest. Can be a GTEx specific ID (e.g. "Whole_Blood"; use get_tissue_site_detail() to see valid values) or an Ontology ID.
datasetId	String. Unique identifier of a dataset. Usually includes a data source and data release. Options: "gtex_v8", "gtex_snrnaseq_pilot".
filterMtGene	Logical. Exclude mitochondrial genes.
page	Integer (default = 0).
itemsPerPage	Integer (default = 250). Set globally to maximum value 100000 with options(list(gtexr.itemsPerPage = 100000)).
.verbose	Logical. If TRUE (default), print paging information. Set to FALSE globally with options(list(gtexr.verbose = FALSE)).
.return_raw	Logical. If TRUE, return the raw API JSON response. Default = FALSE

Value

A tibble. Or a list if .return_raw = TRUE.

See Also

Other Expression Data Endpoints: get_clustered_median_exon_expression(), get_clustered_median_gene_expression(), get_clustered_median_junction_expression(), get_clustered_median_transcript_expression(), get_expression_pca(), get_gene_expression(), get_median_exon_expression(), get_median_gene_expression(), get_median_junction_expression(), get_median_transcript_expression(), get_single_nucleus_gex(), get_single_nucleus_gex_summary()

Examples

## Not run: 
get_top_expressed_genes(tissueSiteDetailId = "Artery_Aorta")

## End(Not run)

gtexr documentation built on June 8, 2025, 10:26 a.m.