The function takes a
SigSet as input, computes detection p-value
using negative control probes parametrized in a normal distribution and
returns a new
SigSet with an updated pval slot.
force rerun even if result already exists
Background of Grn and Red are estimated separately from negative control probes-parameterized normal distribution. p-value is taken from the minimum of the p-value of the two alleles (color depends on probe design).
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