detectionPnegNormGS: Detection P-value emulating Genome Studio

Description Usage Arguments Details Value Examples

View source: R/detection.R

Description

The function takes a SigSet as input, computes detection p-value using negative control probes parametrized in a normal distribution a la Genome Studio and returns a new SigSet with an updated pval slot.

Usage

1

Arguments

sset

a SigSet

force

force rerun even if result already exists

Details

P-value is calculated using negative control probes as the estimate of background where Grn channel and Red channel are merged. But when estimating p-value the Red and Grn are summed (non-ideal).

Value

detection p-value

Examples

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sesame documentation built on Nov. 15, 2020, 2:08 a.m.