noob: Noob background correction

Description Usage Arguments Value Examples

View source: R/background_correction.R

Description

The function takes a SigSet and returns a modified SigSet with background subtracted. Background was modelled in a normal distribution and true signal in an exponential distribution. The Norm-Exp deconvolution is parameterized using Out-Of-Band (oob) probes

Usage

1
noob(sset, oobRprobes = NULL, oobGprobes = NULL, offset = 15)

Arguments

sset

a SigSet

oobRprobes

out-of-band red probes, if not given use all oobR

oobGprobes

out-of-band grn probes, if not given use all oobG

offset

offset

Value

a new SigSet with noob background correction

Examples

1
2
sset <- makeExampleTinyEPICDataSet()
sset.nb <- noob(sset)

sesame documentation built on Nov. 15, 2020, 2:08 a.m.