The package provides a set of functions whose aim is to propose 4 methods of QTL detection:
-HAPimLD is an interval-mapping method designed for unrelated individuals with no family information that makes use of linkage disequilibrium.
-HAPimLDL is an interval-mapping method for design of half-sib families. It combines linkage analysis and linkage disequilibrium.
-HaploMax is based on an analysis of variance with a dose haplotype effect.
-HaploMaxHS is based on an analysis of variance with a sire effect and a dose haplotype effect in half-sib family design.
Fundings for the package development were provided to the LDLmapQTL project by the ANR GENANIMAL program and APIS-GENE.
S. Dejean, N. Oumouhou, D. Estivals, B. Mangin
Maintainer: Brigitte Mangin <[email protected]>
publication to be submitted: C. Cierco-Ayrolles, S. Dejean, A. Legarra, H. Gilbert, T. Druet, F. Ytournel, D. Estivals, N. Oumouhou and B. Mangin. Combining linkage analysis and linkage disequilibrium for QTL fine mapping in animal pedigrees.
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